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N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

Mutations in the NGLY1 (N-glycanase 1) gene, encoding an evolutionarily conserved deglycosylation enzyme, are associated with a rare congenital disorder leading to global developmental delay and neurological abnormalities. The molecular mechanism of the NGLY1 disease and its function in tissue and i...

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Detalles Bibliográficos
Autores principales:	Yang, Kun, Huang, Ryan, Fujihira, Haruhiko, Suzuki, Tadashi, Yan, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170171/ https://www.ncbi.nlm.nih.gov/pubmed/30135079 http://dx.doi.org/10.1084/jem.20180783

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