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Macrophages of distinct origins contribute to tumor development in the lung
Tissue-resident macrophages can self-maintain without contribution of adult hematopoiesis. Herein we show that tissue-resident interstitial macrophages (Res-TAMs) in mouse lungs contribute to the pool of tumor-associated macrophages (TAMs) together with CCR2-dependent recruited macrophages (MoD-TAMs...
Autores principales: | Loyher, Pierre-Louis, Hamon, Pauline, Laviron, Marie, Meghraoui-Kheddar, Aïda, Goncalves, Elena, Deng, Zihou, Torstensson, Sara, Bercovici, Nadège, Baudesson de Chanville, Camille, Combadière, Béhazine, Geissmann, Frederic, Savina, Ariel, Combadière, Christophe, Boissonnas, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170177/ https://www.ncbi.nlm.nih.gov/pubmed/30201786 http://dx.doi.org/10.1084/jem.20180534 |
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