α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster

Damage-associated molecular patterns (DAMPs) are molecules exposed or released by dead cells that trigger or modulate immunity and tissue repair. In vertebrates, the cytoskeletal component F-actin is a DAMP specifically recognised by DNGR-1, an innate immune receptor. Previously we suggested that ac...

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Detalles Bibliográficos
Autores principales: Gordon, Oliver, Henry, Conor M, Srinivasan, Naren, Ahrens, Susan, Franz, Anna, Deddouche, Safia, Chakravarty, Probir, Phillips, David, George, Roger, Kjaer, Svend, Frith, David, Snijders, Ambrosius P, Valente, Rita S, Simoes da Silva, Carolina J, Teixeira, Luis, Thompson, Barry, Dionne, Marc S, Wood, Will, Reis e Sousa, Caetano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170186/
https://www.ncbi.nlm.nih.gov/pubmed/30260317
http://dx.doi.org/10.7554/eLife.38636

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