Insulin regulates POMC neuronal plasticity to control glucose metabolism

Hypothalamic neurons respond to nutritional cues by altering gene expression and neuronal excitability. The mechanisms that control such adaptive processes remain unclear. Here we define populations of POMC neurons in mice that are activated or inhibited by insulin and thereby repress or inhibit hep...

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Detalles Bibliográficos
Autores principales: Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170188/
https://www.ncbi.nlm.nih.gov/pubmed/30230471
http://dx.doi.org/10.7554/eLife.38704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170188/
https://www.ncbi.nlm.nih.gov/pubmed/30230471
http://dx.doi.org/10.7554/eLife.38704

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