Remodeling of lumbar motor circuitry remote to a thoracic spinal cord injury promotes locomotor recovery

Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10) contusive spinal cord injury (SCI) could modulate dendritic...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wu, Wei, Wu, Xiangbing, Sun, Yan, Zhang, Yi P, Deng, Ling-Xiao, Walker, Melissa Jane, Qu, Wenrui, Chen, Chen, Liu, Nai-Kui, Han, Qi, Dai, Heqiao, Shields, Lisa BE, Shields, Christopher B, Sengelaub, Dale R, Jones, Kathryn J, Smith, George M, Xu, Xiao-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170189/
https://www.ncbi.nlm.nih.gov/pubmed/30207538
http://dx.doi.org/10.7554/eLife.39016

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