Cargando…

Markers of Mitochondrial Metabolism in Tumor Hypoxia, Systemic Inflammation, and Adverse Outcome of Rectal Cancer()()

Tumor hypoxia contributes to therapy resistance and metastatic progression of locally advanced rectal cancer (LARC). We postulated that the tumor mitochondrial metabolism, manifested by reactive oxygen species (ROS) and mitochondrial DNA (mtDNA) damage, reflects how hypoxic conditions connect to can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bousquet, Paula A., Meltzer, Sebastian, Sønstevold, Linda, Esbensen, Ying, Dueland, Svein, Flatmark, Kjersti, Sitter, Beathe, Bathen, Tone Frost, Seierstad, Therese, Redalen, Kathrine Røe, Eide, Lars, Ree, Anne Hansen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170256/ https://www.ncbi.nlm.nih.gov/pubmed/30273860 http://dx.doi.org/10.1016/j.tranon.2018.09.010

Ejemplares similares

Immunogenic cell death by neoadjuvant oxaliplatin and radiation protects against metastatic failure in high-risk rectal cancer
por: Bains, Simer J., et al.
Publicado: (2019)

Principal component analysis for the comparison of metabolic profiles from human rectal cancer biopsies and colorectal xenografts using high-resolution magic angle spinning (1)H magnetic resonance spectroscopy
por: Seierstad, Therese, et al.
Publicado: (2008)

Systemic release of osteoprotegerin during oxaliplatin-containing induction chemotherapy and favorable systemic outcome of sequential radiotherapy in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2016)

High level of circulating vitamin D during neoadjuvant therapy may lower risk of metastatic progression in high-risk rectal cancer
por: Abrahamsson, Hanna, et al.
Publicado: (2019)

Early increase in circulating carbonic anhydrase IX during neoadjuvant treatment predicts favourable outcome in locally advanced rectal cancer
por: Hektoen, Helga Helseth, et al.
Publicado: (2015)

Systemic immune response induced by oxaliplatin-based neoadjuvant therapy favours survival without metastatic progression in high-risk rectal cancer
por: Kalanxhi, Erta, et al.
Publicado: (2018)

Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Corrigendum to “Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer” [Transl Oncol 12 (8) (2019) 1038–1044]
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Circulating proteins in response to combined-modality therapy in rectal cancer identified by antibody array screening
por: Kalanxhi, Erta, et al.
Publicado: (2016)

The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
por: Meltzer, Sebastian, et al.
Publicado: (2021)

Sex-related differences in primary metastatic site in rectal cancer; associated with hemodynamic factors?
por: Meltzer, Sebastian, et al.
Publicado: (2019)

Biomarkers of Treatment Toxicity in Combined-Modality Cancer Therapies with Radiation and Systemic Drugs: Study Design, Multiplex Methods, Molecular Networks
por: Ree, Anne Hansen, et al.
Publicado: (2014)

Induction of Apoptosis in Intestinal Toxicity to a Histone Deacetylase Inhibitor in a Phase I Study with Pelvic Radiotherapy
por: Kalanxhi, Erta, et al.
Publicado: (2017)

Sex disparities in vitamin D status and the impact on systemic inflammation and survival in rectal cancer
por: Abrahamsson, Hanna, et al.
Publicado: (2021)

Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy
por: Bratland, Åse, et al.
Publicado: (2011)

Metabolic changes in psoriatic skin under topical corticosteroid treatment
por: Sitter, Beathe, et al.
Publicado: (2013)

Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells
por: Risberg, Karianne, et al.
Publicado: (2016)

Biomarkers of Histone Deacetylase Inhibitor Activity in a Phase 1 Combined-Modality Study with Radiotherapy
por: Ree, Anne Hansen, et al.
Publicado: (2014)

Tumor Phosphatidylinositol-3-Kinase Signaling and Development of Metastatic Disease in Locally Advanced Rectal Cancer
por: Ree, Anne Hansen, et al.
Publicado: (2012)

Energy Metabolism Is Altered in Radioresistant Rectal Cancer
por: Buckley, Croí E., et al.
Publicado: (2023)

The mitochondrial DNA constitution shaping T-cell immunity in patients with rectal cancer at high risk of metastatic progression
por: Bousquet, P. A., et al.
Publicado: (2021)

An experimental strategy unveiling exosomal microRNAs 486-5p, 181a-5p and 30d-5p from hypoxic tumour cells as circulating indicators of high-risk rectal cancer
por: Bjørnetrø, Tonje, et al.
Publicado: (2019)

Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study
por: Røe, Kathrine, et al.
Publicado: (2011)

Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
por: Jonsson, Marte, et al.
Publicado: (2016)

Evaluating the Impact of High Intensity Interval Training on Axial Psoriatic Arthritis Based on MR Images
por: Chronaiou, Ioanna, et al.
Publicado: (2022)

Merging transcriptomics and metabolomics - advances in breast cancer profiling
por: Borgan, Eldrid, et al.
Publicado: (2010)

Metabolic mapping by use of high-resolution magic angle spinning (1)H MR spectroscopy for assessment of apoptosis in cervical carcinomas
por: Lyng, Heidi, et al.
Publicado: (2007)

Hypoxia imaging and theranostic potential of [(64)Cu][Cu(ATSM)] and ionic Cu(II) salts: a review of current evidence and discussion of the retention mechanisms
por: Liu, Tengzhi, et al.
Publicado: (2020)

Comparison of Intravoxel incoherent motion imaging and multiecho dynamic contrast‐based MRI in rectal cancer
por: Bakke, Kine Mari, et al.
Publicado: (2019)

Imaging the tumour microenvironment in rectal cancer: Decline in tumour blood flow during radiotherapy predicts good outcome
por: Bakke, Kine Mari, et al.
Publicado: (2023)

Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy
por: Cao, Maria D, et al.
Publicado: (2012)

Impact of Freezing Delay Time on Tissue Samples for Metabolomic Studies
por: Haukaas, Tonje H., et al.
Publicado: (2016)

Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination
por: Saelen, Marie Grøn, et al.
Publicado: (2011)

Urinary detection of corticosteroid in topical treatment of skin disease by (19)F MRS
por: Sitter, Beathe
Publicado: (2019)

Next-generation sequencing reveals mitogenome diversity in plasma extracellular vesicles from colorectal cancer patients
por: Bjørnetrø, Tonje, et al.
Publicado: (2023)

ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
por: Solbakken, Arne M., et al.
Publicado: (2023)

Future directions on the merge of quantitative imaging and artificial intelligence in radiation oncology
por: Redalen, Kathrine Røe, et al.
Publicado: (2020)

Radiosensitization by the histone deacetylase inhibitor vorinostat under hypoxia and with capecitabine in experimental colorectal carcinoma
por: Saelen, Marie Grøn, et al.
Publicado: (2012)

Feasibility of MR Metabolomics for Immediate Analysis of Resection Margins during Breast Cancer Surgery
por: Bathen, Tone F., et al.
Publicado: (2013)

Development of an automated production process of [(64)Cu][Cu (ATSM)] for positron emission tomography imaging and theranostic applications
por: Liu, Tengzhi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j0hahbd0c85r4bn6tca5dektdq