Spectrum of mitochondrial genome instability and implication of mitochondrial haplogroups in Korean patients with acute myeloid leukemia

BACKGROUND: Mitochondrial DNA (mtDNA) mutations may regulate the progression and chemosensitivity of leukemia. Few studies regarding mitochondrial aberrations and haplogroups in acute myeloid leukemia (AML) and their clinical impacts have been reported. Therefore, we focused on the mtDNA length hete...

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Detalles Bibliográficos
Autores principales: Kim, Hye Ran, Kang, Min-Gu, Lee, Young Eun, Na, Bo Ram, Noh, Min Seo, Yang, Seung Hyun, Shin, Jong-Hee, Shin, Myun-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170299/
https://www.ncbi.nlm.nih.gov/pubmed/30310792
http://dx.doi.org/10.5045/br.2018.53.3.240

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