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Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland
Here we report the discovery and partial characterization of a novel herpesvirus tentatively named Bufonid herpesvirus 1 (BfHV1) from severe dermatitis in free ranging common toads (Bufo bufo) in Switzerland. The disease has been observed in toads every year since 2014, in spring, during the mating...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170376/ https://www.ncbi.nlm.nih.gov/pubmed/30283010 http://dx.doi.org/10.1038/s41598-018-32841-0 |
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author | Origgi, Francesco C. Schmidt, Benedikt R. Lohmann, Petra Otten, Patricia Meier, Roman K. Pisano, Simone R. R. Moore-Jones, Gaia Tecilla, Marco Sattler, Ursula Wahli, Thomas Gaschen, Veronique Stoffel, Michael H. |
author_facet | Origgi, Francesco C. Schmidt, Benedikt R. Lohmann, Petra Otten, Patricia Meier, Roman K. Pisano, Simone R. R. Moore-Jones, Gaia Tecilla, Marco Sattler, Ursula Wahli, Thomas Gaschen, Veronique Stoffel, Michael H. |
author_sort | Origgi, Francesco C. |
collection | PubMed |
description | Here we report the discovery and partial characterization of a novel herpesvirus tentatively named Bufonid herpesvirus 1 (BfHV1) from severe dermatitis in free ranging common toads (Bufo bufo) in Switzerland. The disease has been observed in toads every year since 2014, in spring, during the mating season, at different and distant locations. The virus is found in the skin and occasionally in the brain of infected toads. The genome of the virus is at least 158 Kb long and contains at least 152 open reading frames with a minimal length of 270 nt. The genome of BfHV1 contains all the signature genes that are present in alloherpesviruses. Phylogenetic analysis based on the amino acid sequence of the DNA polymerase and terminase proteins positions the novel virus among the members of the genus Batrachovirus, family Alloherpesviridae. This is the first herpesvirus ever characterized in common toads. |
format | Online Article Text |
id | pubmed-6170376 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61703762018-10-05 Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland Origgi, Francesco C. Schmidt, Benedikt R. Lohmann, Petra Otten, Patricia Meier, Roman K. Pisano, Simone R. R. Moore-Jones, Gaia Tecilla, Marco Sattler, Ursula Wahli, Thomas Gaschen, Veronique Stoffel, Michael H. Sci Rep Article Here we report the discovery and partial characterization of a novel herpesvirus tentatively named Bufonid herpesvirus 1 (BfHV1) from severe dermatitis in free ranging common toads (Bufo bufo) in Switzerland. The disease has been observed in toads every year since 2014, in spring, during the mating season, at different and distant locations. The virus is found in the skin and occasionally in the brain of infected toads. The genome of the virus is at least 158 Kb long and contains at least 152 open reading frames with a minimal length of 270 nt. The genome of BfHV1 contains all the signature genes that are present in alloherpesviruses. Phylogenetic analysis based on the amino acid sequence of the DNA polymerase and terminase proteins positions the novel virus among the members of the genus Batrachovirus, family Alloherpesviridae. This is the first herpesvirus ever characterized in common toads. Nature Publishing Group UK 2018-10-03 /pmc/articles/PMC6170376/ /pubmed/30283010 http://dx.doi.org/10.1038/s41598-018-32841-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Origgi, Francesco C. Schmidt, Benedikt R. Lohmann, Petra Otten, Patricia Meier, Roman K. Pisano, Simone R. R. Moore-Jones, Gaia Tecilla, Marco Sattler, Ursula Wahli, Thomas Gaschen, Veronique Stoffel, Michael H. Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title | Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title_full | Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title_fullStr | Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title_full_unstemmed | Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title_short | Bufonid herpesvirus 1 (BfHV1) associated dermatitis and mortality in free ranging common toads (Bufo bufo) in Switzerland |
title_sort | bufonid herpesvirus 1 (bfhv1) associated dermatitis and mortality in free ranging common toads (bufo bufo) in switzerland |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170376/ https://www.ncbi.nlm.nih.gov/pubmed/30283010 http://dx.doi.org/10.1038/s41598-018-32841-0 |
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