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Reduction of HIP2 expression causes motor function impairment and increased vulnerability to dopaminergic degeneration in Parkinson’s disease models

Huntingtin interaction protein 2 (HIP2) is an E2 ubiquitin-conjugating enzyme associated with neurodegenerative diseases, and HIP2 mRNA has been implicated as a potential blood biomarker for Parkinson’s disease (PD). However, it is unclear whether the alteration of HIP2 expression may contribute to...

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Detalles Bibliográficos
Autores principales:	Su, Jinlin, Huang, Pei, Qin, Meiling, Lu, Qingqing, Sang, Xiao, Cai, Yijun, Wang, Ying, Liu, Fubing, Wu, Rong, Wang, Xiaoping, Jiang, Xiaoxing, Wang, Jian, Sun, Qiang, Chen, Shengdi, Xu, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170399/ https://www.ncbi.nlm.nih.gov/pubmed/30282965 http://dx.doi.org/10.1038/s41419-018-1066-z

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