CPP-Ts: a new intracellular calcium channel modulator and a promising tool for drug delivery in cancer cells

Scorpion sting envenoming impacts millions of people worldwide, with cardiac effects being one of the main causes of death on victims. Here we describe the first Ca(2+) channel toxin present in Tityus serrulatus (Ts) venom, a cell penetrating peptide (CPP) named CPP-Ts. We show that CPP-Ts increases...

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Detalles Bibliográficos
Autores principales: Oliveira-Mendes, Bárbara Bruna Ribeiro de, Horta, Carolina Campolina Rebello, do Carmo, Anderson Oliveira, Biscoto, Gabriela Lago, Sales-Medina, Douglas Ferreira, Leal, Hortênsia Gomes, Brandão-Dias, Pedro Ferreira Pinto, Miranda, Sued Eustáquio Mendes, Aguiar, Carla Jeane, Cardoso, Valbert Nascimento, de Barros, André Luis Branco, Chávez-Olortégui, Carlos, Leite, M. Fátima, Kalapothakis, Evanguedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170434/
https://www.ncbi.nlm.nih.gov/pubmed/30282983
http://dx.doi.org/10.1038/s41598-018-33133-3

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