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LncRNA-MEG3 inhibits activation of hepatic stellate cells through SMO protein and miR-212

Activation of hepatic stellate cells (HSCs), a pivotal event in liver fibrosis, is considered as an epithelial–mesenchymal transition (EMT) process. Deregulation of long noncoding RNAs (lncRNAs) has been reported to be involved in a series of human diseases. LncRNA-maternally expressed gene 3 (MEG3)...

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Detalles Bibliográficos
Autores principales: Yu, Fujun, Geng, Wujun, Dong, Peihong, Huang, Zhiming, Zheng, Jianjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170498/
https://www.ncbi.nlm.nih.gov/pubmed/30282972
http://dx.doi.org/10.1038/s41419-018-1068-x