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Quantifying the phosphorylation timescales of receptor–ligand complexes: a Markovian matrix-analytic approach

Cells interact with the extracellular environment by means of receptor molecules on their surface. Receptors can bind different ligands, leading to the formation of receptor–ligand complexes. For a subset of receptors, called receptor tyrosine kinases, binding to ligand enables sequential phosphoryl...

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Detalles Bibliográficos
Autores principales: López-García, M., Nowicka, M., Bendtsen, C., Lythe, G., Ponnambalam, S., Molina-París, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170503/
https://www.ncbi.nlm.nih.gov/pubmed/30232099
http://dx.doi.org/10.1098/rsob.180126