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Quantifying the phosphorylation timescales of receptor–ligand complexes: a Markovian matrix-analytic approach
Cells interact with the extracellular environment by means of receptor molecules on their surface. Receptors can bind different ligands, leading to the formation of receptor–ligand complexes. For a subset of receptors, called receptor tyrosine kinases, binding to ligand enables sequential phosphoryl...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170503/ https://www.ncbi.nlm.nih.gov/pubmed/30232099 http://dx.doi.org/10.1098/rsob.180126 |