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A spatio-temporal model reveals self-limiting FcɛRI cross-linking by multivalent antigens

Aggregation of cell surface receptor proteins by multivalent antigens is an essential early step for immune cell signalling. A number of experimental and modelling studies in the past have investigated multivalent ligand-mediated aggregation of IgE receptors (FcɛRI) in the plasma membrane of mast ce...

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Detalles Bibliográficos
Autores principales: Shahinuzzaman, Md, Khetan, Jawahar, Barua, Dipak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170560/
https://www.ncbi.nlm.nih.gov/pubmed/30839725
http://dx.doi.org/10.1098/rsos.180190