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An Atomistic Model of a Precursor State of Light-Induced Channel Opening of Channelrhodopsin
Channelrhodopsins (ChRs) are microbial light-gated ion channels with a retinal chromophore and are widely utilized in optogenetics to precisely control neuronal activity with light. Despite increasing understanding of their structures and photoactivation kinetics, the atomistic mechanism of light ga...
Autores principales: | Cheng, Cheng, Kamiya, Motoshi, Takemoto, Mizuki, Ishitani, Ryuichiro, Nureki, Osamu, Yoshida, Norio, Hayashi, Shigehiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170652/ https://www.ncbi.nlm.nih.gov/pubmed/30236783 http://dx.doi.org/10.1016/j.bpj.2018.08.024 |
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