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Mapping Determinants of Cytokine Signaling via Protein Engineering

Cytokines comprise a large family of secreted ligands that are critical for the regulation of immune homeostasis. Cytokines initiate signaling via dimerization or oligomerization of the cognate receptor subunits, triggering the activation of the Janus Kinases (JAKs)/ signal transducer and activator...

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Detalles Bibliográficos
Autores principales:	Gorby, Claire, Martinez-Fabregas, Jonathan, Wilmes, Stephan, Moraga, Ignacio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170656/ https://www.ncbi.nlm.nih.gov/pubmed/30319612 http://dx.doi.org/10.3389/fimmu.2018.02143

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