Synthetic Fragments of Receptor for Advanced Glycation End Products Bind Beta-Amyloid 1–40 and Protect Primary Brain Cells From Beta-Amyloid Toxicity

Receptor for advanced glycation end products (RAGE) is involved in the pathogenesis of Alzheimer’s disease. We have previously revealed that RAGE fragment sequence (60–76) and its shortened analogs sequence (60–70) and (60–65) under intranasal insertion were able to restore memory and improve morpho...

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Detalles Bibliográficos
Autores principales: Kamynina, Anna V., Esteras, Noemi, Koroev, Dmitriy O., Bobkova, Natalia V., Balasanyants, Samson M., Simonyan, Ruben A., Avetisyan, Armine V., Abramov, Andrey Y., Volpina, Olga M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170785/
https://www.ncbi.nlm.nih.gov/pubmed/30319347
http://dx.doi.org/10.3389/fnins.2018.00681

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