The non-reconstructive treatment of complete ACL tear with biological enhancement in clinical and preclinical studies: A systematic review

INTRODUCTION: There is still controversy regarding the bio-enhanced non-reconstructive ACL treatment. MATERIALS AND METHODS: A search for articles in databases was performed in February 2017. The objective and subjective evaluations of clinical studies and biomechanical and histological data of prec...

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Detalles Bibliográficos
Autores principales: Li, Yue, Fu, Sai Cheun, Cheuk, Yau Chuk, Song, Guanyang, Feng, Hua, Yung, Shu-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia-Pacific Knee, Arthroscopy and Sports Medicine Society 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170796/
https://www.ncbi.nlm.nih.gov/pubmed/30302314
http://dx.doi.org/10.1016/j.asmart.2018.04.002
Descripción
Sumario:INTRODUCTION: There is still controversy regarding the bio-enhanced non-reconstructive ACL treatment. MATERIALS AND METHODS: A search for articles in databases was performed in February 2017. The objective and subjective evaluations of clinical studies and biomechanical and histological data of preclinical studies were extracted. RESULTS: Eighteen articles were included for analysis. In clinical studies, although subjective scores were significantly improved, the rate of re-operation rate was high. In preclinical studies, bio-enhancing techniques demonstrated promotion of the healing of ACL. CONCLUSIONS: The efficacy of biological enhancement cannot be validated in clinical studies. Preclinical studies showed improved biomechanical and healing potential.

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