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MYC Amplification as a Potential Mechanism of Primary Resistance to Crizotinib in ALK-Rearranged Non-Small Cell Lung Cancer: A Brief Report()()

INTRODUCTION: Translocations of the anaplastic lymphoma kinase (ALK) can be effectively targeted in advanced non-small cell lung cancer by ALK-TKI inhibitors including Crizotinib. However, the development of acquired resistance often limits the duration of these therapies. While several mechanisms o...

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Detalles Bibliográficos
Autores principales:	Rihawi, Karim, Alfieri, Roberta, Fiorentino, Michelangelo, Fontana, Francesca, Capizzi, Elisa, Cavazzoni, Andrea, Terracciano, Mario, La Monica, Silvia, Ferrarini, Alberto, Buson, Genny, Petronini, Pier Giorgio, Ardizzoni, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2018
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171095/ https://www.ncbi.nlm.nih.gov/pubmed/30290287 http://dx.doi.org/10.1016/j.tranon.2018.09.013

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