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Phenotype of vigilin expressing breast cancer cells binding to the 69 nt 3′UTR element in CSF-1R mRNA

Vigilin, a nucleocytoplasmic shuttling protein, post-transcriptionally suppresses proto-oncogene c-fms expression (encoding CSF-1R) in breast cancer by binding to a 69 nt cis-acting 3-UTR element in CSF-1R mRNA. CSF-1R is an important mediator of breast cancer development, metastasis, and survival....

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Detalles Bibliográficos
Autores principales: Woo, Ho-Hyung, Lee, Sang C., Stoffer, Jha’nae B., Rush, Demaretta, Chambers, Setsuko K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171096/
https://www.ncbi.nlm.nih.gov/pubmed/30292064
http://dx.doi.org/10.1016/j.tranon.2018.09.012

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