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Disruption of Chromosomal Architecture of cox2 Locus Sensitizes Lung Cancer Cells to Radiotherapy

Despite treatment of lung cancer with radiotherapy and chemotherapy, the survival rate of lung cancer patients remains poor. Previous studies demonstrated the importance of upregulation of inflammatory factors, such as cyclooxygenase 2 (cox2), in tumor tolerance. In the present study, we investigate...

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Detalles Bibliográficos
Autores principales: Sun, Yuxiang, Dai, Hui, Chen, Shaopeng, Zhang, Yajun, Wu, Tao, Cao, Xianbin, Zhao, Guoping, Xu, An, Wang, Jun, Wu, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171098/
https://www.ncbi.nlm.nih.gov/pubmed/30131302
http://dx.doi.org/10.1016/j.ymthe.2018.08.002