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Surgical peritoneal stress creates a pro-metastatic niche promoting resistance to apoptosis via IL-8
BACKGROUND: The mainstay of treatment of advanced ovarian cancer (AOC) involves chemotherapy, and debulking surgery. However, despite optimal surgical procedure and adjuvant chemotherapy, 60% of patients with AOC will relapse within 5 years. Most recurrences occur in the peritoneal cavity, suggestin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171219/ https://www.ncbi.nlm.nih.gov/pubmed/30285881 http://dx.doi.org/10.1186/s12967-018-1643-z |