UBN1/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells

BACKGROUND: H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. However, it still remains largely uncharacterized how HIRA complex specifically re...

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Detalles Bibliográficos
Autores principales: Xiong, Chaoyang, Wen, Zengqi, Yu, Juan, Chen, Jun, Liu, Chao-Pei, Zhang, Xiaodong, Chen, Ping, Xu, Rui-Ming, Li, Guohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171237/
https://www.ncbi.nlm.nih.gov/pubmed/30285846
http://dx.doi.org/10.1186/s12915-018-0573-9

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