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Impaired Liver Function Implied Shorter Progression Free Survival for EGFR Tyrosine Kinase Inhibitors

BACKGROUND: Epithelial growth factor receptor tyrosine kinase inhibitor (EGFR TKI) revolutionize the standard of care for advanced non-small cell lung cancer (NSCLC) harboring sensitive EGFR mutation. Liver toxicity is the dose-limiting factor for TKI but its importance is largely overlooked. Here t...

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Detalles Bibliográficos
Autores principales:	Zhu, Qi-Qi, Wang, Chun, Chen, Yue-Yun, Ding, Zhen-Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171407/ https://www.ncbi.nlm.nih.gov/pubmed/30139222 http://dx.doi.org/10.22034/APJCP.2018.19.8.2177

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