Carbonic anhydrase inhibition with a series of novel benzenesulfonamide-triazole conjugates

We report the synthesis and characterisation of a novel series of triazole benzenesulfonamide derivatives, which incorporate the general pharmacophore associated with carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. The synthesised compounds were tested in vitro against four human carbonic anhydrase...

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Detalles Bibliográficos
Autores principales: El-Gazzar, Marwa G., Nafie, Nessma H., Nocentini, Alessio, Ghorab, Mostafa M., Heiba, Helmi I., Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171417/
https://www.ncbi.nlm.nih.gov/pubmed/30274535
http://dx.doi.org/10.1080/14756366.2018.1513927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171417/
https://www.ncbi.nlm.nih.gov/pubmed/30274535
http://dx.doi.org/10.1080/14756366.2018.1513927

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