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Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state

The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism. The structural basis of the light activation mechanism of this protein remains unclear. In this work, ful...

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Detalles Bibliográficos
Autores principales: Rinaldi, Jimena, Fernández, Ignacio, Poth, Lucía M., Shepard, William E., Savko, Martin, Goldbaum, Fernando A., Klinke, Sebastián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171537/
https://www.ncbi.nlm.nih.gov/pubmed/30294679
http://dx.doi.org/10.1016/j.bbrep.2018.09.005