Functional Annotation of ESR1 Gene Fusions in Estrogen Receptor-Positive Breast Cancer

RNA sequencing (RNA-seq) detects estrogen receptor alpha gene (ESR1) fusion transcripts in estrogen receptor-positive (ER(+)) breast cancer, but their role in disease pathogenesis remains unclear. We examined multiple ESR1 fusions and found that two, both identified in advanced endocrine treatment-r...

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Detalles Bibliográficos
Autores principales: Lei, Jonathan T., Shao, Jieya, Zhang, Jin, Iglesia, Michael, Chan, Doug W., Cao, Jin, Anurag, Meenakshi, Singh, Purba, He, Xiaping, Kosaka, Yoshimasa, Matsunuma, Ryoichi, Crowder, Robert, Hoog, Jeremy, Phommaly, Chanpheng, Goncalves, Rodrigo, Ramalho, Susana, Rodrigues Peres, Raquel Mary, Punturi, Nindo, Schmidt, Cheryl, Bartram, Alex, Jou, Eric, Devarakonda, Vaishnavi, Holloway, Kimberly R., Lai, W. Victoria, Hampton, Oliver, Rogers, Anna, Tobias, Ethan, Parikh, Poojan A., Davies, Sherri R., Li, Shunqiang, Ma, Cynthia X., Suman, Vera J., Hunt, Kelly K., Watson, Mark A., Hoadley, Katherine A., Thompson, E. Aubrey, Chen, Xi, Kavuri, Shyam M., Creighton, Chad J., Maher, Christopher A., Perou, Charles M., Haricharan, Svasti, Ellis, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171747/
https://www.ncbi.nlm.nih.gov/pubmed/30089255
http://dx.doi.org/10.1016/j.celrep.2018.07.009

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