Cargando…
Tumorigenicity-associated characteristics of human iPS cell lines
Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs containing residual undifferentiated hiPSCs may cause tum...
Autores principales: | Yasuda, Satoshi, Kusakawa, Shinji, Kuroda, Takuya, Miura, Takumi, Tano, Keiko, Takada, Nozomi, Matsuyama, Satoko, Matsuyama, Akifumi, Nasu, Michiyo, Umezawa, Akihiro, Hayakawa, Takao, Tsutsumi, Hideki, Sato, Yoji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171902/ https://www.ncbi.nlm.nih.gov/pubmed/30286143 http://dx.doi.org/10.1371/journal.pone.0205022 |
Ejemplares similares
-
SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation
por: Kuroda, Takuya, et al.
Publicado: (2019) -
Identification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells
por: Kuroda, Takuya, et al.
Publicado: (2017) -
Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells
por: Kuroda, Takuya, et al.
Publicado: (2015) -
Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγ(null) mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products
por: Kusakawa, Shinji, et al.
Publicado: (2015) -
Single-Cell RNA-Seq Reveals LRRC75A-Expressing Cell Population Involved in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia
por: Miura, Takumi, et al.
Publicado: (2023)