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LC3B is not recruited along with the autophagy elongation complex (ATG5-12/16L1) at HCV replication site and is dispensable for viral replication

Hepatitis C virus (HCV) infection is known to induce autophagosome accumulation as observed by the typical punctate cytoplasmic distribution of LC3B-II in infected cells. Previously, we showed that viral RNA-dependent RNA polymerase (NS5B) interacts with ATG5, a major component of the autophagy elon...

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Detalles Bibliográficos
Autores principales: Fahmy, Ahmed M., Khabir, Marwa, Blanchet, Matthieu, Labonté, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171931/
https://www.ncbi.nlm.nih.gov/pubmed/30286180
http://dx.doi.org/10.1371/journal.pone.0205189

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