Identification of KLF9 and BCL3 as transcription factors that enhance reprogramming of primordial germ cells

Primordial germ cells (PGCs) are precursors of eggs and sperm. Although PGCs are unipotent cells in vivo, they are reprogrammed into pluripotent stem cells (PSCs), also known as embryonic germ cells (EGCs), in the presence of leukemia inhibitory factor and basic fibroblast growth factor (bFGF) in vi...

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Detalles Bibliográficos
Autores principales: Otsuka, Kei, Takehara, Asuka, Chiba, Natsuko, Matsui, Yasuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171932/
https://www.ncbi.nlm.nih.gov/pubmed/30286177
http://dx.doi.org/10.1371/journal.pone.0205004

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