Cargando…
Combined effect of cabozantinib and gefitinib in crizotinib‐resistant lung tumors harboring ROS1 fusions
The ROS1 tyrosine kinase inhibitor (TKI) crizotinib has shown dramatic effects in patients with non‐small cell lung cancer (NSCLC) harboring ROS1 fusion genes. However, patients inevitably develop resistance to this agent. Therefore, a new treatment strategy is required for lung tumors with ROS1 fus...
Autores principales: | Kato, Yuka, Ninomiya, Kiichiro, Ohashi, Kadoaki, Tomida, Shuta, Makimoto, Go, Watanabe, Hiromi, Kudo, Kenichiro, Matsumoto, Shingo, Umemura, Shigeki, Goto, Koichi, Ichihara, Eiki, Ninomiya, Takashi, Kubo, Toshio, Sato, Akiko, Hotta, Katsuyuki, Tabata, Masahiro, Toyooka, Shinichi, Maeda, Yoshinobu, Kiura, Katsuyuki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172052/ https://www.ncbi.nlm.nih.gov/pubmed/30053332 http://dx.doi.org/10.1111/cas.13752 |
Ejemplares similares
-
MET or NRAS amplification is an acquired resistance mechanism to the third-generation EGFR inhibitor naquotinib
por: Ninomiya, Kiichiro, et al.
Publicado: (2018) -
Successful and Prompt Treatment with Tepotinib for Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation Combined with Lung Abscess Formation: A Case Report
por: Makimoto, Go, et al.
Publicado: (2022) -
Clinical significance of repeat rebiopsy in detecting the EGFR T790M secondary mutation in patients with non-small cell lung cancer
por: Ichihara, Eiki, et al.
Publicado: (2018) -
Identification of targetable kinases in idiopathic pulmonary fibrosis
por: Higo, Hisao, et al.
Publicado: (2022) -
Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M in vivo
por: Kudo, Kenichiro, et al.
Publicado: (2017)