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Leptin Increases Particle-Induced Osteolysis in Female ob/obMice

Particles generated from wear of prosthesis joint bearing surfaces induce inflammation-mediated periprosthetic bone resorption (osteolysis). Morbidly obese leptin-deficient ob/ob mice are resistant to polyethylene particle-induced bone loss, suggesting that leptin, a hormone produced by adipocytes t...

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Detalles Bibliográficos
Autores principales:	Philbrick, Kenneth A., Branscum, Adam J., Wong, Carmen P., Turner, Russell T., Iwaniec, Urszula T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172200/ https://www.ncbi.nlm.nih.gov/pubmed/30287858 http://dx.doi.org/10.1038/s41598-018-33173-9

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