Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans

Mild inhibition of mitochondrial respiration leads to longevity. Disruption of mitochondrial respiratory components extends lifespan in Caenorhabditis elegans, but the effects appear to be complex and the underlying mechanism for lifespan regulation by mitochondrial respiratory genes is still not fu...

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Detalles Bibliográficos
Autores principales: Xu, Chen, Hwang, Wooseon, Jeong, Dae-Eun, Ryu, Youngjae, Ha, Chang Man, Lee, Seung-Jae V., Liu, Lulu, He, Zhi Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172204/
https://www.ncbi.nlm.nih.gov/pubmed/30287841
http://dx.doi.org/10.1038/s41598-018-32025-w

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