Cargando…

Systematic expression alteration analysis of master reprogramming factor OCT4 and its three pseudogenes in human cancer and their prognostic outcomes

OCT4 is a master transcription factor that regulates the pluripotency of pluripotent stem cells and cancer stem cells along with other factors, including SOX2, KLF4, and C-MYC. Three different transcripts, OCT4A, OCT4B, and OCT4B1, are known to be generated by alternative splicing and eight OCT4 pse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saha, Subbroto Kumar, Jeong, Yeojin, Cho, Sungha, Cho, Ssang-Goo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172215/ https://www.ncbi.nlm.nih.gov/pubmed/30287838 http://dx.doi.org/10.1038/s41598-018-33094-7

Ejemplares similares

Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
por: Lee, Moonjung, et al.
Publicado: (2023)

Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
por: Saha, Subbroto Kumar, et al.
Publicado: (2018)

Systematic Multiomics Analysis of Alterations in C1QBP mRNA Expression and Relevance for Clinical Outcomes in Cancers
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

High Expression of TTYH3 Is Related to Poor Clinical Outcomes in Human Gastric Cancer
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Opposing Regulation of Cancer Properties via KRT19-Mediated Differential Modulation of Wnt/β-Catenin/Notch Signaling in Breast and Colon Cancers
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Improved Isolation and Culture of Urine-Derived Stem Cells (USCs) and Enhanced Production of Immune Cells from the USC-Derived Induced Pluripotent Stem Cells
por: Kim, Kyeongseok, et al.
Publicado: (2020)

G protein-coupled receptors in stem cell maintenance and somatic reprogramming to pluripotent or cancer stem cells
por: Choi, Hye Yeon, et al.
Publicado: (2015)

Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer
por: Chae, Hee Sung, et al.
Publicado: (2020)

Multi-Omics Analysis of SOX4, SOX11, and SOX12 Expression and the Associated Pathways in Human Cancers
por: Seok, Jaekwon, et al.
Publicado: (2021)

PROM1 and PROM2 expression differentially modulates clinical prognosis of cancer: a multiomics analysis
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Prognostic role of EGR1 in breast cancer: a systematic review
por: Saha, Subbroto Kumar, et al.
Publicado: (2021)

Expression of ATP/GTP Binding Protein 1 Has Prognostic Value for the Clinical Outcomes in Non-Small Cell Lung Carcinoma
por: Kwak, Hee Jeong, et al.
Publicado: (2020)

The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms
por: Abdal Dayem, Ahmed, et al.
Publicado: (2016)

Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells
por: Saha, Subbroto Kumar, et al.
Publicado: (2017)

Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells
por: Kawser Hossain, Mohammed, et al.
Publicado: (2016)

GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17
por: Saha, Subbroto Kumar, et al.
Publicado: (2020)

Correlation between Oxidative Stress, Nutrition, and Cancer Initiation
por: Saha, Subbroto Kumar, et al.
Publicado: (2017)

Differential Expression of OCT4 Pseudogenes in Pluripotent and Tumor Cell Lines
por: Poursani, Ensieh M., et al.
Publicado: (2016)

The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles
por: Abdal Dayem, Ahmed, et al.
Publicado: (2017)

Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells
por: Hossain, Mohammed Kawser, et al.
Publicado: (2018)

Molecular Insights Into Therapeutic Potential of Autophagy Modulation by Natural Products for Cancer Stem Cells
por: Rahman, Md. Ataur, et al.
Publicado: (2020)

Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
por: Kawser Hossain, Mohammed, et al.
Publicado: (2016)

Expression and Differentiation between OCT4A and Its Pseudogenes in Human ESCs and Differentiated Adult Somatic Cells
por: Jez, Mojca, et al.
Publicado: (2014)

Bioinformatics Approach for Identifying Novel Biomarkers and Their Signaling Pathways Involved in Interstitial Cystitis/Bladder Pain Syndrome with Hunner Lesion
por: Saha, Subbroto Kumar, et al.
Publicado: (2020)

Epigenetic silencing of Oct4 by a complex containing SUV39H1 and Oct4 pseudogene lncRNA
por: Scarola, Michele, et al.
Publicado: (2015)

Production of Mesenchymal Stem Cells through Stem Cell Reprogramming
por: Abdal Dayem, Ahmed, et al.
Publicado: (2019)

Correction: Expression and Differentiation between OCT4A and Its Pseudogenes in Human ESCs and Differentiated Adult Somatic Cells
Publicado: (2014)

Human haematopoietic stem cells express Oct4 pseudogenes and lack the ability to initiate Oct4 promoter-driven gene expression
por: Redshaw, Zoe, et al.
Publicado: (2010)

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities
por: Choi, Hye Yeon, et al.
Publicado: (2019)

Pseudogenes
por: Tutar, Yusuf
Publicado: (2012)

FUS-dependent loading of SUV39H1 to OCT4 pseudogene-lncRNA programs a silencing complex with OCT4 promoter specificity
por: Scarola, Michele, et al.
Publicado: (2020)

Identification of Potential Diagnostic and Prognostic Pseudogenes in Hepatocellular Carcinoma Based on Pseudogene-miRNA-mRNA Competitive Network
por: Yan, Lijun, et al.
Publicado: (2020)

Improved Wound Healing and Skin Regeneration Ability of 3,2′-Dihydroxyflavone-Treated Mesenchymal Stem Cell-Derived Extracellular Vesicles
por: Kim, Sehee, et al.
Publicado: (2023)

Reprogramming competence of OCT factors is determined by transactivation domains
por: Kim, Kee-Pyo, et al.
Publicado: (2020)

Biological importance of OCT transcription factors in reprogramming and development
por: Kim, Kee-Pyo, et al.
Publicado: (2021)

The Orphan GPR50 Receptor Regulates the Aggressiveness of Breast Cancer Stem-like Cells via Targeting the NF-kB Signaling Pathway
por: Biswas, Polash Kumar, et al.
Publicado: (2023)

Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation
por: Karro, John E., et al.
Publicado: (2007)

Imprinted gene Zinc finger protein 127 is a novel regulator of master pluripotency transcription factor, Oct4
por: Kwon, Yoo-Wook, et al.
Publicado: (2018)

The GENCODE pseudogene resource
por: Pei, Baikang, et al.
Publicado: (2012)

Pseudogenes in Human Cancer
por: Poliseno, Laura, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4f2eudd1menjaskjv7g87828o3