Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1

The Na(+)/H(+) exchanger NHE1 is critical for cell vitality as it controls intracellular pH and cell volume. Its functionality is influenced by calcineurin B homologous proteins (CHPs). The human isoform CHP3 is important for transport of NHE1 to the plasma membrane and for its activity. Here, we ch...

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Detalles Bibliográficos
Autores principales: Fuchs, Simon, Hansen, Sierra C., Markones, Marie, Mymrikov, Evgeny V., Heerklotz, Heiko, Hunte, Carola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172220/
https://www.ncbi.nlm.nih.gov/pubmed/30287853
http://dx.doi.org/10.1038/s41598-018-33096-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172220/
https://www.ncbi.nlm.nih.gov/pubmed/30287853
http://dx.doi.org/10.1038/s41598-018-33096-5

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