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Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes
Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with bo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172275/ https://www.ncbi.nlm.nih.gov/pubmed/30287830 http://dx.doi.org/10.1038/s41598-018-32407-0 |
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author | Li, Jiawen Fejes, Peter Lorenser, Dirk Quirk, Bryden C. Noble, Peter B. Kirk, Rodney W. Orth, Antony Wood, Fiona M. Gibson, Brant C. Sampson, David D. McLaughlin, Robert A. |
author_facet | Li, Jiawen Fejes, Peter Lorenser, Dirk Quirk, Bryden C. Noble, Peter B. Kirk, Rodney W. Orth, Antony Wood, Fiona M. Gibson, Brant C. Sampson, David D. McLaughlin, Robert A. |
author_sort | Li, Jiawen |
collection | PubMed |
description | Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical function and dimensions comparable to the optical fibre diameter. Recently, major advances in two-photon direct laser writing have enabled 3D printing of arbitrary three-dimensional micro/nanostructures with a surface roughness acceptable for optical applications. Here, we demonstrate the feasibility of 3D printing of OCT probes. We evaluate the capability of this method based on a series of characterisation experiments. We report fabrication of a micro-optic containing an off-axis paraboloidal total internal reflecting surface, its integration as part of a common-path OCT probe, and demonstrate proof-of-principle imaging of biological samples. |
format | Online Article Text |
id | pubmed-6172275 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61722752018-10-09 Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes Li, Jiawen Fejes, Peter Lorenser, Dirk Quirk, Bryden C. Noble, Peter B. Kirk, Rodney W. Orth, Antony Wood, Fiona M. Gibson, Brant C. Sampson, David D. McLaughlin, Robert A. Sci Rep Article Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical function and dimensions comparable to the optical fibre diameter. Recently, major advances in two-photon direct laser writing have enabled 3D printing of arbitrary three-dimensional micro/nanostructures with a surface roughness acceptable for optical applications. Here, we demonstrate the feasibility of 3D printing of OCT probes. We evaluate the capability of this method based on a series of characterisation experiments. We report fabrication of a micro-optic containing an off-axis paraboloidal total internal reflecting surface, its integration as part of a common-path OCT probe, and demonstrate proof-of-principle imaging of biological samples. Nature Publishing Group UK 2018-10-04 /pmc/articles/PMC6172275/ /pubmed/30287830 http://dx.doi.org/10.1038/s41598-018-32407-0 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Li, Jiawen Fejes, Peter Lorenser, Dirk Quirk, Bryden C. Noble, Peter B. Kirk, Rodney W. Orth, Antony Wood, Fiona M. Gibson, Brant C. Sampson, David D. McLaughlin, Robert A. Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title | Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title_full | Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title_fullStr | Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title_full_unstemmed | Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title_short | Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes |
title_sort | two-photon polymerisation 3d printed freeform micro-optics for optical coherence tomography fibre probes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172275/ https://www.ncbi.nlm.nih.gov/pubmed/30287830 http://dx.doi.org/10.1038/s41598-018-32407-0 |
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