Germline pathogenic variants of 11 breast cancer genes in 7,051 Japanese patients and 11,241 controls

Pathogenic variants in highly penetrant genes are useful for the diagnosis, therapy, and surveillance for hereditary breast cancer. Large-scale studies are needed to inform future testing and variant classification processes in Japanese. We performed a case-control association study for variants in...

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Detalles Bibliográficos
Autores principales: Momozawa, Yukihide, Iwasaki, Yusuke, Parsons, Michael T., Kamatani, Yoichiro, Takahashi, Atsushi, Tamura, Chieko, Katagiri, Toyomasa, Yoshida, Teruhiko, Nakamura, Seigo, Sugano, Kokichi, Miki, Yoshio, Hirata, Makoto, Matsuda, Koichi, Spurdle, Amanda B., Kubo, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172276/
https://www.ncbi.nlm.nih.gov/pubmed/30287823
http://dx.doi.org/10.1038/s41467-018-06581-8

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