Cargando…

Single dose moxidectin versus ivermectin for Onchocerca volvulus infection in Ghana, Liberia, and the Democratic Republic of the Congo: a randomised, controlled, double-blind phase 3 trial

BACKGROUND: The morbidity and socioeconomic effects of onchocerciasis, a parasitic disease that is primarily endemic in sub-Saharan Africa, have motivated large morbidity and transmission control programmes. Annual community-directed ivermectin treatment has substantially reduced prevalence. Elimina...

Descripción completa

Detalles Bibliográficos
Autores principales:	Opoku, Nicholas O, Bakajika, Didier K, Kanza, Eric M, Howard, Hayford, Mambandu, Germain L, Nyathirombo, Amos, Nigo, Maurice M, Kasonia, Kambale, Masembe, Safari L, Mumbere, Mupenzi, Kataliko, Kambale, Larbelee, Jemmah P, Kpawor, Mawolo, Bolay, Kpehe M, Bolay, Fatorma, Asare, Sampson, Attah, Simon K, Olipoh, George, Vaillant, Michel, Halleux, Christine M, Kuesel, Annette C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172290/ https://www.ncbi.nlm.nih.gov/pubmed/29361335 http://dx.doi.org/10.1016/S0140-6736(17)32844-1

Ejemplares similares

Effect of a single dose of 8 mg moxidectin or 150 μg/kg ivermectin on O. volvulus skin microfilariae in a randomized trial: Differences between areas in the Democratic Republic of the Congo, Liberia and Ghana and impact of intensity of infection
por: Bakajika, Didier, et al.
Publicado: (2022)

Can mass drug administration of moxidectin accelerate onchocerciasis elimination in Africa?
por: Kura, Klodeta, et al.
Publicado: (2023)

Sirenomelia associated with an anterior abdominal wall defect: a case report
por: Kavunga, Eric Kambale, et al.
Publicado: (2019)

Huge scalp Morel-Lavallée lesion with eye involvement in a 3-year-old girl: a case report
por: Masumbuko, Claude Kasereka, et al.
Publicado: (2021)

Xenosurveillance reflects traditional sampling techniques for the identification of human pathogens: A comparative study in West Africa
por: Fauver, Joseph R., et al.
Publicado: (2018)

Newborn screening for sickle cell disease in Butembo and Beni: a pilot experience in a highland region of the Democratic Republic of Congo
por: Mumbere, Mupenzi, et al.
Publicado: (2023)

Antimicrobial resistance in a war-torn country: Lessons learned in the Eastern Democratic Republic of the Congo
por: Bunduki, Gabriel Kambale, et al.
Publicado: (2019)

Pharmacokinetics of oral moxidectin in individuals with Onchocerca volvulus infection
por: Tan, Beesan, et al.
Publicado: (2022)

Filling the Gap 115 Years after Ronald Ross: The Distribution of the Anopheles coluzzii and Anopheles gambiae s.s from Freetown and Monrovia, West Africa
por: de Souza, Dziedzom K., et al.
Publicado: (2013)

Correction: Filling the Gap 115 Years after Ronald Ross: The Distribution of the Anopheles coluzzii and Anopheles gambiae s.s from Freetown and Monrovia, West Africa
por: de Souza, Dziedzom K., et al.
Publicado: (2014)

Solvatomorphism of Moxidectin
por: Grell, Toni, et al.
Publicado: (2021)

Impact of Annual versus Semiannual Mass Drug Administration with Ivermectin and Albendazole on Helminth Infections in Southeastern Liberia
por: Eneanya, Obiora A., et al.
Publicado: (2022)

A Randomized, Single-Ascending-Dose, Ivermectin-Controlled, Double-Blind Study of Moxidectin in Onchocerca volvulus Infection
por: Awadzi, Kwablah, et al.
Publicado: (2014)

Community trust of government and non-governmental organizations during the 2014-16 Ebola epidemic in Liberia
por: Arthur, Ronan F., et al.
Publicado: (2022)

Early Experiences in the Integration of Non-communicable Diseases into Emergency Primary Health Care, Beni Region, Democratic Republic of the Congo
por: Ratnayake, Ruwan, et al.
Publicado: (2021)

Thalamocortical network interruption: A fresh view for migraine symptoms
por: BOLAY, Hayrunnisa
Publicado: (2020)

One month follow up of a neonate born to a mother who survived Ebola virus disease during pregnancy: a case report in the Democratic Republic of Congo
por: Baraka, N. Kasereka, et al.
Publicado: (2019)

Late abdominal pregnancy in a post-conflict context: case of a mistaken acute abdomen - a case report
por: Paluku, Justin Lussy, et al.
Publicado: (2020)

Capillaria Ova and Diagnosis of Trichuris trichiura Infection in Humans by Kato-Katz Smear, Liberia
por: Fischer, Kerstin, et al.
Publicado: (2018)

The potential impact of moxidectin on onchocerciasis elimination in Africa: an economic evaluation based on the Phase II clinical trial data
por: Turner, Hugo C, et al.
Publicado: (2015)

Community Attitudes toward Mass Drug Administration for Control and Elimination of Neglected Tropical Diseases after the 2014 Outbreak of Ebola Virus Disease in Lofa County, Liberia
por: Bogus, Joshua, et al.
Publicado: (2016)

Ebola in the Eastern Democratic Republic of Congo: One Health approach to infectious disease control
por: Sikakulya, Franck katembo, et al.
Publicado: (2019)

Management of severe acute malnutrition by cow milk in resource constraints settings: experience of the Nutritional Centre of the University Clinics of Graben
por: Mumbere, Mupenzi, et al.
Publicado: (2018)

Comparative Evaluation of Marginal Adaptation and Fracture Strength of Different Ceramic Inlays Produced by CEREC Omnicam and Heat-Pressed Technique
por: Oz, F. D., et al.
Publicado: (2018)

Frontiers of cosmopolitanism: Educational enclaves and the extractive roots of international schools
por: Bolay, Matthieu, et al.
Publicado: (2021)

Untargeted Metabolite Profiling of Specialty Rice Grains Using Gas Chromatography Mass Spectrometry
por: Kambale, Rohit, et al.
Publicado: (2022)

Synophtalmia on a newborn
por: Bihamba Bira, Laetitia, et al.
Publicado: (2022)

Pre-Ebola virus disease laboratory system and related challenges in Liberia
por: Kennedy, Stephen B., et al.
Publicado: (2016)

The laboratory health system and its response to the Ebola virus disease outbreak in Liberia
por: Kennedy, Stephen B., et al.
Publicado: (2016)

Fine needle aspiration-induced vascular proliferation of the thyroid: A report of two cases
por: Ramraje, Sushma N., et al.
Publicado: (2012)

Cognitive dysfunction and migraine
por: Vuralli, Doga, et al.
Publicado: (2018)

Barriers and Opportunities for Sustainable Hand Hygiene Interventions in Rural Liberian Hospitals
por: Tantum, Lucy K., et al.
Publicado: (2021)

Clinical outcome and isolated pathogens among neonates with sepsis in Democratic Republic of the Congo: a cross-sectional study
por: Bunduki, Gabriel Kambale, et al.
Publicado: (2019)

The usefulness of C-reactive protein as a biomarker in predicting neonatal sepsis in a sub-Saharan African region
por: Bunduki, Gabriel Kambale, et al.
Publicado: (2020)

Aura and Head pain: relationship and gaps in the translational models
por: Bolay, Hayrunnisa, et al.
Publicado: (2019)

Cosmopolitan enclaves: An introduction
por: Rey, Jeanne, et al.
Publicado: (2021)

Subacute sclerosing panencephalitis: A clinical appraisal
por: Jagtap, Sujit Abajirao, et al.
Publicado: (2013)

Sacral agenesis with club shaped conus
por: Jagtap, Sujit Abajirao, et al.
Publicado: (2013)

EHMTI-0353. MR tractography in short lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) patients: case reports
por: Coskun, O, et al.
Publicado: (2014)

Creative use of the priority review voucher by public and not-for-profit actors delivers the first new FDA-approved treatment for river blindness in 20 years
por: Olliaro, Piero L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ncead6dhg8u4qkojr031g07fel