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Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment
The neonatal Fc receptor (FcRn) is responsible for the recycling and transcytosis of IgG and albumin. FcRn level was found altered in cancer tissues and implicated in tumor immunosurveillance and neoplastic cell growth. However, the consequences of FcRn down-regulation in the anti-tumor immune respo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172308/ https://www.ncbi.nlm.nih.gov/pubmed/30323819 http://dx.doi.org/10.3389/fimmu.2018.02259 |