Lack of FcRn Impairs Natural Killer Cell Development and Functions in the Tumor Microenvironment

The neonatal Fc receptor (FcRn) is responsible for the recycling and transcytosis of IgG and albumin. FcRn level was found altered in cancer tissues and implicated in tumor immunosurveillance and neoplastic cell growth. However, the consequences of FcRn down-regulation in the anti-tumor immune respo...

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Detalles Bibliográficos
Autores principales: Castaneda, Diana Cadena, Dhommée, Christine, Baranek, Thomas, Dalloneau, Emilie, Lajoie, Laurie, Valayer, Alexandre, Arnoult, Christophe, Demattéi, Marie-Véronique, Fouquenet, Delphine, Parent, Christelle, Heuzé-Vourc'h, Nathalie, Gouilleux-Gruart, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172308/
https://www.ncbi.nlm.nih.gov/pubmed/30323819
http://dx.doi.org/10.3389/fimmu.2018.02259

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