Reduced Excitability and Increased Neurite Complexity of Cortical Interneurons in a Familial Mouse Model of Amyotrophic Lateral Sclerosis

Cortical interneurons play a crucial role in regulating inhibitory-excitatory balance in brain circuits, filtering synaptic information and dictating the activity of pyramidal cells through the release of GABA. In the fatal motor neuron (MN) disease, amyotrophic lateral sclerosis (ALS), an imbalance...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Rosemary M., Brizuela, Mariana, Blizzard, Catherine A., Dickson, Tracey C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172321/
https://www.ncbi.nlm.nih.gov/pubmed/30323744
http://dx.doi.org/10.3389/fncel.2018.00328

Ejemplares similares

Ejemplares similares