KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control

Endogenous retroviruses (ERVs) have accumulated in vertebrate genomes and contribute to the complexity of gene regulation. KAP1 represses ERVs during development by its recruitment to their repetitive sequences through KRAB zinc‐finger proteins (KZNFs), but little is known about the regulation of ER...

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Detalles Bibliográficos
Autores principales: Tie, Christopher HC, Fernandes, Liane, Conde, Lucia, Robbez‐Masson, Luisa, Sumner, Rebecca P, Peacock, Tom, Rodriguez‐Plata, Maria Teresa, Mickute, Greta, Gifford, Robert, Towers, Greg J, Herrero, Javier, Rowe, Helen M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172469/
https://www.ncbi.nlm.nih.gov/pubmed/30061100
http://dx.doi.org/10.15252/embr.201745000

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