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Exogenous spermidine ameliorates tubular necrosis during cisplatin nephrotoxicity
The hallmark of cisplatin-induced acute kidney injury is the necrotic cell death in the kidney proximal tubules. However, an effective approach to limit cisplatin nephrotoxicity remains unknown. Spermidine is a polyamine that protects against oxidative stress and necrosis in aged yeasts, and the pre...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Association of Anatomists
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172597/ https://www.ncbi.nlm.nih.gov/pubmed/30310711 http://dx.doi.org/10.5115/acb.2018.51.3.189 |