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NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis

Endogenous glutamate (Glu) release and N-methyl-d-aspartate (NMDA) receptor (NMDAR) activation are associated with lung injury in different animal models. However, the underlying mechanism is unclear. Bone marrow-derived mesenchymal stem cells (BM-MSCs), which show potential use for immunomodulation...

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Detalles Bibliográficos
Autores principales: Li, Xiaohong, Li, Chen, Tang, Yiting, Huang, Yanhong, Cheng, Qingmei, Huang, Xiaoting, Zhao, Feiyan, Hao, Caixia, Feng, Dandan, Xu, Jianping, Han, Jianzhong, Tang, Siyuan, Liu, Wei, Yue, Shaojie, Luo, Ziqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172623/
https://www.ncbi.nlm.nih.gov/pubmed/29722562
http://dx.doi.org/10.1152/ajplung.00002.2018