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Self-nanoemulsifying system improves oral absorption and enhances anti-acute myeloid leukemia activity of berberine

BACKGROUND: Recently, we found that berberine (BBR) exerts anti-acute myeloid leukemia activity, particularly toward high-risk and relapsed/refractory acute myeloid leukemia MV4-11 cells in vitro. However, the poor water solubility and low bioavailability observed with oral BBR administration has li...

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Detalles Bibliográficos
Autores principales:	Li, Jieping, Yang, Li, Shen, Rui, Gong, Li, Tian, Zhiqiang, Qiu, Huarong, Shi, Zhe, Gao, Lichen, Sun, Hongwu, Zhang, Guangsen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172716/ https://www.ncbi.nlm.nih.gov/pubmed/30290822 http://dx.doi.org/10.1186/s12951-018-0402-x

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