Liposomal formulations of carboplatin injected by convection-enhanced delivery increases the median survival time of F98 glioma bearing rats

BACKGROUND: Effectiveness of chemotherapy for treating glioblastoma (GBM) brain tumors is hampered by the blood–brain barrier which limits the entry into the brain of most drugs from the blood. To bypass this barrier, convection-enhanced delivery (CED) was proposed to directly inject drugs in tumor....

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Detalles Bibliográficos
Autores principales: Shi, Minghan, Anantha, Malathi, Wehbe, Mohamed, Bally, Marcel B., Fortin, David, Roy, Laurent-Olivier, Charest, Gabriel, Richer, Maxime, Paquette, Benoit, Sanche, Léon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172733/
https://www.ncbi.nlm.nih.gov/pubmed/30290821
http://dx.doi.org/10.1186/s12951-018-0404-8

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