Time to death and risk factors among tuberculosis patients in Northern Ethiopia

OBJECTIVE: The main objective of this study was to assess time to death and associated risk factors among tuberculosis (TB) patients. RESULTS: A total of 769 TB patients were studied and of those, 87 (11.3%) patients died. All of the deaths occurred within 7 months of anti-tuberculosis therapy. Extr...

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Detalles Bibliográficos
Autores principales: Asgedom, Solomon Weldegebreal, Tesfaye, Daniel, Nirayo, Yirga Legesse, Atey, Tesfay Mehari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172746/
https://www.ncbi.nlm.nih.gov/pubmed/30286801
http://dx.doi.org/10.1186/s13104-018-3806-7
Descripción
Sumario:OBJECTIVE: The main objective of this study was to assess time to death and associated risk factors among tuberculosis (TB) patients. RESULTS: A total of 769 TB patients were studied and of those, 87 (11.3%) patients died. All of the deaths occurred within 7 months of anti-tuberculosis therapy. Extra-pulmonary TB (AHR = 17.376, 95% CI; 3.88–77.86, p < 0.001) as compared to pulmonary TB and cotrimoxazole prophylaxis therapy (CPT) (AHR = 0.15, 95% CI; 0.03–0.74, p = 0.02) were found to be the predictors of mortality. We noticed higher rates of mortality. Extra-pulmonary TB patients have high risk and TB-HIV co-infected patients who received CPT have low risk of death. Improving early diagnosis of extra-pulmonary TB and early CPT initiation of TB-HIV co-infected patients could minimize patient’s mortality. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3806-7) contains supplementary material, which is available to authorized users.

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