Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells

BACKGROUND: Osteosarcoma is the most common bone cancer. Despite advances, molecular mechanisms associated with osteosarcoma have not been fully understood. Hence, an effective treatment for osteosarcoma has yet to be developed. Even though signal transducer and activator of transcription3 (STAT3) h...

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Detalles Bibliográficos
Autores principales: Zuo, Dongqing, Shogren, Kristen L, Zang, Jie, Jewison, Donna E, Waletzki, Brian E, Miller, Alan L, Okuno, Scott H, Cai, Zhengdong, Yaszemski, Michael J, Maran, Avudaiappan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172747/
https://www.ncbi.nlm.nih.gov/pubmed/30286779
http://dx.doi.org/10.1186/s13046-018-0914-0

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