Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

BACKGROUND: In spite of major advances in treatment, multiple myeloma (MM) is currently an incurable malignancy due to the emergence of drug-resistant clones. We previously showed that MM cells upregulate the transcriptional repressor, growth factor independence 1 (Gfi1), in bone marrow stromal cell...

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Detalles Bibliográficos
Autores principales: Petrusca, Daniela N, Toscani, Denise, Wang, Feng-Ming, Park, Cheolkyu, Crean, Colin D, Anderson, Judith L, Marino, Silvia, Mohammad, Khalid S, Zhou, Dan, Silbermann, Rebecca, Sun, Quanhong, Kurihara, Noriyoshi, Galson, Deborah L, Giuliani, Nicola, Roodman, G David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172782/
https://www.ncbi.nlm.nih.gov/pubmed/30286780
http://dx.doi.org/10.1186/s13045-018-0666-5

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