Cargando…

Inhibition of WEE1 Suppresses the Tumor Growth in Laryngeal Squamous Cell Carcinoma

WEE1 is a tyrosine kinase that regulates G2/M cell cycle checkpoint and frequently overexpressed in various tumors. However, the expression and clinical significance of WEE1 in human laryngeal squamous cell carcinoma (LSCC) are still unknown. In this study, we found that WEE1 was highly expressed in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Meng-Ling, Li, Pei, Xing, Zi-Hao, Di, Jin-Ming, Liu, Hui, Yang, An-Kui, Lin, Xi-Jun, Jiang, Qi-Wei, Yang, Yang, Huang, Jia-Rong, Wang, Kun, Wei, Meng-Ning, Li, Yao, Ye, Jin, Shi, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172786/ https://www.ncbi.nlm.nih.gov/pubmed/30323762 http://dx.doi.org/10.3389/fphar.2018.01041

Ejemplares similares

MiR-194 functions as a tumor suppressor in laryngeal squamous cell carcinoma by targeting Wee1
por: Li, Pei, et al.
Publicado: (2017)

miR-936 Suppresses Cell Proliferation, Invasion, and Drug Resistance of Laryngeal Squamous Cell Carcinoma and Targets GPR78
por: Lin, Xi-Jun, et al.
Publicado: (2020)

Reciprocal regulation of miR-1205 and E2F1 modulates progression of laryngeal squamous cell carcinoma
por: Li, Pei, et al.
Publicado: (2019)

Wee1 Inhibitor AZD1775 Effectively Inhibits the Malignant Phenotypes of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo
por: Bi, Shuning, et al.
Publicado: (2019)

Regulatory Mechanisms of lncRNAs and Their Target Gene Signaling Pathways in Laryngeal Squamous Cell Carcinoma
por: Li, Wei, et al.
Publicado: (2020)

Long Noncoding RNA TRPM2-AS Promotes the Growth, Migration, and Invasion of Retinoblastoma via miR-497/WEE1 Axis
por: Li, Aipeng, et al.
Publicado: (2021)

Piperlongumine Alleviates Mouse Colitis and Colitis-Associated Colorectal Cancer
por: Huang, Jia-Rong, et al.
Publicado: (2020)

Evaluation of the Expression of Matrix Metalloproteinase-1 of Laryngeal Squamous Cell Carcinoma by Ultrasound Molecular Imaging
por: Zhou, Yi, et al.
Publicado: (2019)

CENPE promotes glioblastomas proliferation by directly binding to WEE1
por: Ma, Chuanling, et al.
Publicado: (2020)

Scopoletin Suppresses Activation of Dendritic Cells and Pathogenesis of Experimental Autoimmune Encephalomyelitis by Inhibiting NF-κB Signaling
por: Zhang, Fei, et al.
Publicado: (2019)

TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation
por: Wan, Yue-Meng, et al.
Publicado: (2020)

Corrigendum: Scopoletin Suppresses Activation of Dendritic Cells and Pathogenesis of Experimental Autoimmune Encephalomyelitis by Inhibiting NF-κB Signaling
por: Zhang, Fei, et al.
Publicado: (2019)

Corrigendum: TSG-6 Inhibits Oxidative Stress and Induces M2 Polarization of Hepatic Macrophages in Mice With Alcoholic Hepatitis via Suppression of STAT3 Activation
por: Wan, Yue-Meng, et al.
Publicado: (2020)

A Simple Clinical Pre-procedure Risk Model for Predicting Thrombocytopenia Associated With Periprocedural Use of Tirofiban in Patients Undergoing Percutaneous Coronary Intervention
por: Yi, Yi-Hu, et al.
Publicado: (2018)

Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma
por: Huang, Shan-Zhou, et al.
Publicado: (2019)

Oxymatrine and Cisplatin Synergistically Enhance Anti-tumor Immunity of CD8(+) T Cells in Non-small Cell Lung Cancer
por: Ye, Jin, et al.
Publicado: (2018)

A novel risk model of three SUMOylation genes based on RNA expression for potential prognosis and treatment sensitivity prediction in kidney cancer
por: Li, Song-Chao, et al.
Publicado: (2023)

Relationship Between the Free and Total Methotrexate Plasma Concentration in Children and Application to Predict the Toxicity of HD-MTX
por: Dong, Wei-Chong, et al.
Publicado: (2021)

Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice
por: Yang, Yang, et al.
Publicado: (2021)

Roles of Major RNA Adenosine Modifications in Head and Neck Squamous Cell Carcinoma
por: Huo, Xing-xing, et al.
Publicado: (2021)

Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer
por: Yang, Hui-Wen, et al.
Publicado: (2023)

Recent Advances of WEE1 Inhibitors and Statins in Cancers With p53 Mutations
por: Meng, Xiangbing, et al.
Publicado: (2021)

Reactivation of mutant p53 in esophageal squamous cell carcinoma by isothiocyanate inhibits tumor growth
por: Guan, Lulu, et al.
Publicado: (2023)

Hypericum perforatum L. Regulates Glutathione Redox Stress and Normalizes Ggt1/Anpep Signaling to Alleviate OVX-Induced Kidney Dysfunction
por: Liu, Yan-Ru, et al.
Publicado: (2021)

Dioscin Promotes Prostate Cancer Cell Apoptosis and Inhibits Cell Invasion by Increasing SHP1 Phosphorylation and Suppressing the Subsequent MAPK Signaling Pathway
por: He, Shuyun, et al.
Publicado: (2020)

Prognostic value of body mass index before treatment for laryngeal squamous cell carcinoma
por: Li, Zhao-Qu, et al.
Publicado: (2015)

Therapeutic Applications of Functional Nanomaterials for Prostatitis
por: Liu, Chun-Ping, et al.
Publicado: (2021)

SHP2 inhibition improves celastrol-induced growth suppression of colorectal cancer
por: Zhang, Linxi, et al.
Publicado: (2022)

Expression Profile and Prognostic Values of HOXA Family Members in Laryngeal Squamous Cell Cancer
por: Li, Jinyun, et al.
Publicado: (2020)

The role of novel programmed cell death in head and neck squamous cell carcinoma: from mechanisms to potential therapies
por: Xi, Yujie, et al.
Publicado: (2023)

Impact of Gastric H(+)/K(+)-ATPase rs2733743 on the Intragastric pH-Values of Dexlansoprazole Injection in Chinese Subjects
por: Sun, Lu-Ning, et al.
Publicado: (2017)

Protocatechuic Aldehyde Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Nox-Mediated Oxidative Stress and Renal Inflammation
por: Gao, Li, et al.
Publicado: (2016)

The underlying molecular mechanism and identification of transcription factor markers for laryngeal squamous cell carcinoma
por: Mo, Bin-Yu, et al.
Publicado: (2021)

Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR
por: Huang, Jun-ming, et al.
Publicado: (2018)

Poria cum Radix Pini Rescues Barium Chloride-Induced Arrhythmia by Regulating the cGMP-PKG Signalling Pathway Involving ADORA1 in Zebrafish
por: Yang, Ning-Juan, et al.
Publicado: (2021)

Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer
por: Chen, Xi, et al.
Publicado: (2022)

Corrigendum: Ulinastatin Inhibits Osteoclastogenesis and Suppresses Ovariectomy-Induced Bone Loss by Downregulating uPAR
por: Huang, Jun-ming, et al.
Publicado: (2018)

A novel necroptosis-related LncRNA signature for prediction of prognosis and therapeutic responses of head and neck squamous cell carcinoma
por: Meng, Zilu, et al.
Publicado: (2022)

Breviscapine remodels myocardial glucose and lipid metabolism by regulating serotonin to alleviate doxorubicin-induced cardiotoxicity
por: Li, Meng-Jiao, et al.
Publicado: (2022)

Neuroprotective Effects of the Anti-cancer Drug Lapatinib Against Epileptic Seizures via Suppressing Glutathione Peroxidase 4-Dependent Ferroptosis
por: Jia, Ji-Ning, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_vf2019d6btbq34t9vl0nr23rrh